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[Pyogenic infections with different locations caused by Streptococcus anginosus alone or in association with
G Coman1, C Pânzaru, D Diculencu
1Disciplina de Microbiologie, U. M. F., Iaşi.
Abstract:
Isolation and identification of S. anginosus from pathologic products are possible to be realised in informed clinical laboratory, allowing so a better knowledge of these infections' incidences and on adequate treatment. The authors' report 11 cases of pyogenic infection caused by S. anginosus. Five out of these 11 cases evaluated as mixed infections, S. anginosus being associated with anaerobic bacteria. 10 children hospitalised in surgery Department of Children Hospital had infections with different localisations; necrotizing fasciitis, preknee cap abscess, generalised peritonitis, abscess postappendectomy, pleurisy and acute mediastinitis, knee arthritis, acute osteomyelitis of mandible and an infection of the fracture's focus in upper 1/3 of the thigh bone. For all these patients the favoring factor was represented by a traumatic or surgical lesion of the skin or diverse mucosa; oral, oesophageal, intestinal, allowing the access of the normal flora of these covers to normally sterile sites. The eleventh case was an adult with a lung abscess and pleurisy, as a complication of an aspiration pneumonia. The treatment of S. anginosus infections consisted especially in penicillin or ampicillin, associated with metronidazol when anaerobic bacteria were present.
Insights
Streptococcus anginosus (S. anginosus) can cause serious pyogenic infections, often linked to trauma or surgery. Early laboratory identification and appropriate antibiotic treatment, including penicillin or ampicillin, are crucial for managing these infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Pathology
Context:
- Streptococcus anginosus group (SAG) bacteria are part of the normal human flora.
- SAG can cause a variety of pyogenic infections, particularly in immunocompromised individuals or following breaches in mucosal barriers.
- Understanding the incidence and clinical spectrum of S. anginosus infections is essential for effective patient management.
Purpose:
- To report on 11 cases of pyogenic infections caused by Streptococcus anginosus.
- To highlight the clinical presentations, predisposing factors, and treatment outcomes of these infections.
- To emphasize the importance of laboratory identification for guiding therapeutic strategies.
Summary:
- Eleven cases of pyogenic infections attributed to Streptococcus anginosus are presented.
- Ten cases involved children with diverse infections (necrotizing fasciitis, abscesses, peritonitis, osteomyelitis, etc.), often following traumatic or surgical lesions.
- Five cases were mixed infections involving anaerobic bacteria. One adult case presented with lung abscess and pleurisy secondary to aspiration pneumonia.
- Treatment primarily involved penicillin or ampicillin, with metronidazole added for mixed anaerobic infections.
Impact:
- Successful isolation and identification of S. anginosus in clinical laboratories improve understanding of infection incidence.
- This knowledge aids in selecting appropriate antimicrobial therapies, improving patient outcomes.
- The study underscores the role of S. anginosus as a pathogen, especially in post-traumatic or post-surgical settings.