Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intraoperative esophageal manometry: our experience

A Del Genio1, G Izzo, N Di Martino

  • 1Department of Digestive Surgery, School of Medicine, Second University of Naples, Italy.

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
|February 10, 1998
PubMed
Summary

Intraoperative esophageal manometry (IEM) improves outcomes in functional esophageal surgery by verifying lower esophageal sphincter (LES) pressure and calibrating fundal wraps. Routine IEM use enhances postoperative results, detecting incomplete myotomies and guiding wrap pressure for better patient recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Thymic hyperplasia is accurate to detect new-onset Graves' hyperthyroidism and resolves after restoring euthyroidism.

Journal of endocrinological investigation·2025
Same author

Variability in autism spectrum phenotypes linked to heterozygous missense familial ANK2 mutation.

European journal of medical genetics·2025
Same author

Thymic hyperplasia is accurate to detect new-onset Graves' hyperthyroidism and resolves after restoring euthyroidism.

Journal of endocrinological investigation·2024
Same author

Gentle Giant? Giant Gastric Solitary Peutz-Jeghers Polyp.

Digestive diseases and sciences·2024
Same author

The role of the foam formulation in improving psoriasis treatment acceptability: a real-life experience and a literature review.

European review for medical and pharmacological sciences·2023
Same author

Comparison of the use of life cycle assessment and ecological footprint methods for evaluating environmental performances in dairy production.

The Science of the total environment·2023

Area of Science:

  • Gastroenterology and Surgical Innovation
  • Esophageal Motility Disorders and Surgical Management

Background:

  • Functional esophageal surgery aims to improve patient outcomes through precise procedural execution.
  • Previous approaches to fundoplication calibration led to high rates of gastroesophageal reflux recurrence.
  • Intraoperative esophageal manometry (IEM) was developed to address limitations in surgical precision for esophageal procedures.

Purpose of the Study:

  • To evaluate the utility and impact of intraoperative esophageal manometry (IEM) in functional esophageal surgery.
  • To assess IEM's role in documenting lower esophageal sphincter (LES) pressure changes and calibrating fundal wraps.
  • To determine if routine IEM improves postoperative outcomes in patients undergoing Heller's myotomy and Nissen-Rossetti fundoplication.

Main Methods:

Related Experiment Videos

  • Intraoperative esophageal manometry (IEM) was applied during 309 functional esophageal surgical procedures since 1985.
  • The study analyzed data from 281 patients: 144 with achalasia (Heller's myotomy + Nissen-Rossetti fundoplication) and 137 with GER-D (Nissen-Rossetti fundoplication).
  • IEM was used to confirm LES high-pressure zone (HPZ) ablation and calibrate fundal wrap pressure ('hypercalibrated Nissen': 20-40 mmHg).

Main Results:

  • IEM detected persistent high-pressure zones (HPZ) in 15.2% of myotomies initially deemed complete by intraoperative endoscopy.
  • The 'hypercalibrated Nissen' approach, guided by IEM, showed promising results, contrasting with earlier 'normocalibrated' attempts that yielded 28.5% GER recurrence.
  • While generally effective, unexplained findings included GER recurrence with hypotonic wraps and dysphagia with excessively high wrap pressures in a few cases.

Conclusions:

  • Intraoperative esophageal manometry (IEM) is a valuable tool for enhancing functional esophageal surgery.
  • Routine IEM use appears to improve postoperative results by ensuring accurate LES pressure management and fundoplication calibration.
  • The 'hypercalibrated Nissen' technique, facilitated by IEM, offers a method to optimize surgical outcomes for esophageal motility disorders and reflux disease.