Related Experiment Videos
Chiral capillary electrophoresis with noncyclic oligo- and polysaccharide chiral selectors
R M Sutton1, K L Sutton, A M Stalcup
1Department of Chemistry, University of Cincinnati, OH 45221-0172, USA.
Electrophoresis
|February 10, 1998
Abstract:
A number of noncyclic oligo- and polysaccharides have been used as chiral additives in capillary electrophoresis (CE). This review offers a broad survey of the types of oligo- and polysaccharides which have been investigated and also some of the conditions developed for the enantioseparation of a wide range of drugs and other racemic compounds. Details of enantioseparation mechanisms are also discussed, in addition to some of the parameters required for optimization of the enantioresolution of chiral molecules.