Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comprehensive multimodality blood conservation: 100 consecutive CABG operations without transfusion

R E Helm1, T K Rosengart, M Gomez

  • 1Department of Cardiothoracic Surgery, The New York Hospital-Cornell Medical Center, New York 10021, USA.

The Annals of Thoracic Surgery
|February 10, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Melanosis of the esophagus: A rare entity.

Revista de gastroenterologia de Mexico (English)·2025
Same author

Pre-and post-surgical non-functional pituitary adenomas and their relationship with high levels of serum glucose.

The International journal of neuroscience·2024
Same author

Long-Term Outcomes of Bovine versus Porcine Mitral Valve Replacement: A Multicenter Analysis.

Cardiology research and practice·2023
Same author

Pre- and post-clinical-radiological and surgical evaluation of patients with pituitary adenoma and metabolic syndrome.

The International journal of neuroscience·2023
Same author

'Atherothrombosis-associated microRNAs in Antiphospholipid syndrome and Systemic Lupus Erythematosus patients'.

Scientific reports·2016
Same author

Public resource usage in health systems: a data envelopment analysis of the efficiency of health systems of autonomous communities in Spain.

Public health·2016
Same journal

Coronary Artery Bypass Grafting versus Percutaneous Coronary Intervention for Stable Multivessel Coronary Disease in the Current Era.

The Annals of thoracic surgery·2026
Same journal

Should the DeBakey Classification Be Reconsidered for Acute Type A Aortic Dissection?

The Annals of thoracic surgery·2026
Same journal

A Health Tracking Application Leads to An Avid Cyclist Being Diagnosed with ALCAPA at 52 years old, Warranting a Takeuchi Repair.

The Annals of thoracic surgery·2026
Same journal

Impact of preoperative and postoperative modern guideline-directed medical therapy on survival following coronary artery bypass grafting.

The Annals of thoracic surgery·2026
Same journal

Does prior percutaneous coronary revascularization negatively affect the outcomes of subsequent coronary artery bypass grafting?

The Annals of thoracic surgery·2026
Same journal

Lymph Node Dissection and Chylothorax - Balancing Oncologic Benefit Against Morbidity.

The Annals of thoracic surgery·2026
See all related articles

A comprehensive blood conservation program significantly reduced bleeding and the need for allogeneic transfusions in coronary artery bypass grafting patients. This approach proved safe, cost-effective, and minimized postoperative blood loss.

Area of Science:

  • Cardiovascular Surgery
  • Transfusion Medicine
  • Healthcare Management

Background:

  • Bleeding and allogeneic transfusions remain significant challenges in open-heart surgery despite existing conservation methods.
  • A hypothesis proposed that a structured, risk-based multimodality blood conservation program could effectively reduce these issues.

Purpose of the Study:

  • To evaluate the efficacy and safety of a risk factor-based multimodality blood conservation program in coronary artery bypass grafting (CABG).
  • To assess the cost-effectiveness of this comprehensive blood conservation strategy compared to standard care.

Main Methods:

  • A prospective study enrolled 100 patients undergoing CABG into a multimodality blood conservation program (MMD group).
  • A control group of 90 CABG patients received standard care but followed identical transfusion guidelines.

Related Experiment Videos

  • Cost-effectiveness was analyzed by comparing MMD patients with diagnostic-related group-matched controls.

    • Main Results:

    • No allogeneic transfusions were required in the 100 MMD group patients.
    • The control group received an average of 2.2 units of allogeneic blood per patient, with 38% receiving transfusions.
    • Postoperative blood loss at 12 hours was significantly lower in the MMD group (370 mL) compared to the control group (660 mL) (p < 0.001).
    • The MMD group demonstrated equivalent or lower total costs across major diagnostic-related groups.

    Conclusions:

    • An integrated, algorithmic application of a comprehensive, risk factor-based blood conservation program significantly reduces bleeding and transfusion needs in CABG.
    • This multimodality approach is safe and cost-effective for managing blood conservation in cardiac surgery.