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Capsule opacification after refilling the capsule with an inflatable endocapsular balloon
1Nishi Eye Hospital, Osaka, Japan.
Journal of Cataract and Refractive Surgery
|February 11, 1998
Summary
Refilling lens capsules with an inflatable balloon caused significant opacification, especially without lens epithelial cell removal. Taut refilling and cell removal reduced opacification but did not fully prevent it.
Area of Science:
- Ophthalmology
- Biomaterials Science
- Veterinary Ophthalmology
Background:
- Capsule opacification is a common complication after intraocular lens implantation.
- Inflatable endocapsular balloons offer a novel approach for lens refilling.
Purpose of the Study:
- To characterize capsule opacification in rabbits and primates after endocapsular balloon refilling.
- To evaluate the impact of refilling techniques and lens epithelial cell (LEC) removal on opacification.
Main Methods:
- Capsule opacification was assessed via slitlamp, Miyake view, and histopathology.
- Studies involved 15 rabbit eyes and 16 primate eyes over 4-32 months.
- Evaluated effects of taut, moderate, and poor refilling, with and without LEC removal.
Main Results:
- A high incidence (94%) of capsule opacification was observed.
- Opacification severity correlated with refilling tension and LEC presence.
- LEC removal generally reduced opacification, with complete clearance in two cases.
Conclusions:
- Taut capsule refilling and LEC removal effectively mitigate, but do not eliminate, capsule opacification.
- Further research into more effective LEC removal or pharmaceutical interventions is warranted.
- This study provides insights into managing capsule opacification in novel lens refilling techniques.