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Pulmonary inflammatory pseudotumor: radiologic features
G A Agrons1, M L Rosado-de-Christenson, W M Kirejczyk
1Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC, USA.
Radiology
|February 11, 1998
Summary
Pulmonary inflammatory pseudotumor typically presents as a solitary, peripheral mass, often in the lower lobes. Unusual cases may show local invasion or mediastinal involvement.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Pulmonary inflammatory pseudotumor is a rare benign lung lesion.
- Accurate radiologic characterization is crucial for diagnosis and management.
Purpose of the Study:
- To define the characteristic radiologic features of pulmonary inflammatory pseudotumor.
- To differentiate pseudotumor from malignant lung neoplasms.
Main Methods:
- Retrospective review of 61 cases of pulmonary inflammatory pseudotumor diagnosed between 1966 and 1994.
- Analysis of clinical presentation, pathological findings, and radiologic imaging (radiography, CT, MRI).
Main Results:
- Solitary peripheral nodules or masses were observed in 52 patients.
- Hilar, mediastinal, and airway invasion occurred in 11 patients.
- CT revealed heterogeneous (12 lesions) and homogeneous (5 lesions) attenuation; MRI showed intermediate to high signal intensity and diffuse enhancement.
Conclusions:
- Pulmonary inflammatory pseudotumor typically appears as a solitary, peripheral, sharply circumscribed mass, favoring lower lobes.
- Local invasion and mediastinal/hilar involvement are uncommon presentations.
- Radiologic features, combined with clinical and pathological data, aid in diagnosis.