Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brachytherapy in lung cancer

L E Gaspar1

  • 1Department of Radiation Oncology, Wayne State University, Detroit, Michigan, USA.

Journal of Surgical Oncology
|February 11, 1998
PubMed
Summary

Brachytherapy delivers high radiation doses directly to tumors. While interstitial brachytherapy is rarely used, endobronchial brachytherapy offers palliative relief for lung cancer symptoms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microscopic and macroscopic tumor and parenchymal effects of liver stereotactic body radiotherapy.

International journal of radiation oncology, biology, physics·2008
Same author

Implant volume as a prognostic variable in brachytherapy decision-making for malignant gliomas stratified by the RTOG recursive partitioning analysis.

International journal of radiation oncology, biology, physics·2001
Same author

Swallowing function and weight change observed in a phase I/II study of external-beam radiation, brachytherapy and concurrent chemotherapy in localized cancer of the esophagus (RTOG 9207).

Cancer journal (Sudbury, Mass.)·2001
Same author

Pulmonary sequelae after electron spinal irradiation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2001
Same author

Optimizing chemoradiation therapy approaches to unresectable stage III non--small cell lung cancer.

Current opinion in oncology·2001
Same author

Pre-irradiation evaluation and management of brain metastases. American College of Radiology. ACR Appropriateness Criteria.

Radiology·2000

Area of Science:

  • Oncology
  • Radiation Therapy
  • Medical Physics

Background:

  • Brachytherapy involves placing radioactive isotopes directly into the tumor bed.
  • It achieves higher doses to the tumor than surrounding normal tissues.
  • Interstitial brachytherapy is infrequently used in clinical practice.

Purpose of the Study:

  • To evaluate the efficacy of endobronchial brachytherapy as a boost to external beam radiation for inoperable lung cancer.
  • To assess brachytherapy's role in palliating obstructive symptoms and hemoptysis.

Main Methods:

  • Review of clinical applications and outcomes of brachytherapy in lung cancer.
  • Comparison of endobronchial brachytherapy combined with external beam radiation versus external beam radiation alone.
  • Analysis of symptom relief in palliative brachytherapy cases.

Main Results:

  • Endobronchial brachytherapy as a boost did not improve local tumor control or survival compared to external beam radiation alone in definitive treatment.
  • Brachytherapy effectively provides prompt relief of obstructive symptoms and hemoptysis in the majority of palliative care patients.

Conclusions:

  • Endobronchial brachytherapy shows limited benefit as a definitive treatment boost for inoperable lung cancer.
  • Brachytherapy is a valuable palliative option for managing obstructive lung cancer symptoms and bleeding.

Related Experiment Videos