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Quinolone-resistant Salmonella paratyphi B meningitis in a newborn: a case report
1Department of Paediatrics, The Aga Khan University Medical Center, Karachi, Pakistan.
The Journal of Infection
|February 12, 1998
Abstract:
While there are concerns about the consequences of widespread use of quinolones, there are few reports of quinolone-resistant strains of Salmonella typhi or Salmonella paratyphi from the Indian subcontinent. We present a case report of a newborn with meningitis due to a quinolone-resistant strain of S. paratyphi B presenting to the Aga Khan University Hospital (AKUH).
Insights
Quinolone-resistant Salmonella paratyphi B caused meningitis in a newborn in the Indian subcontinent. This case highlights emerging antimicrobial resistance concerns in the region.
Area of Science:
- Infectious Diseases
- Microbiology
- Pharmacology
Background:
- Widespread quinolone use raises concerns about antimicrobial resistance.
- Limited reports exist of quinolone-resistant Salmonella typhi and Salmonella paratyphi from the Indian subcontinent.
Observation:
- A newborn presented with meningitis at Aga Khan University Hospital.
- The meningitis was caused by a strain of Salmonella paratyphi B.
Findings:
- The identified Salmonella paratyphi B strain exhibited resistance to quinolones.
- This represents a rare occurrence of quinolone resistance in this pathogen from the region.
Implications:
- This case underscores the growing threat of antimicrobial resistance in common pathogens.
- It highlights the need for enhanced surveillance of quinolone-resistant Salmonella in the Indian subcontinent.
- Clinical management strategies may need re-evaluation in light of emerging resistance patterns.