Intraocular cancers

1. Retinoblastoma is the most common primary intraocular cancer of children. It occurs in unilateral and bilateral forms. 2. Approximately 40% of all cases are associated with a heritable defect in chromosome 13. 3. Malignant melanoma is the most common primary intraocular malignant tumor among adults. 4. Unlike retinoblastoma, primary intraocular malignant melanoma is almost exclusively a monocular, unifocal disease without hereditary transmission.