Related Experiment Video
Updated: Aug 17, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
A longitudinal study of hospitalization rates for patients with chronic disease: results from the Medical Outcomes
E C Nelson1, C A McHorney, W G Manning
1Community and Family Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
Objective:
To prospectively compare inpatient and outpatient utilization rates between prepaid (PPD) and fee-for-service (FFS) insurance coverage for patients with chronic disease.
Data Source/Study Setting:
Data from the Medical Outcomes Study, a longitudinal observational study of chronic disease patients conducted in Boston, Chicago, and Los Angeles.
Study Design:
A four-year prospective study of resource utilization among 1,681 patients under treatment for hypertension, diabetes, myocardial infarction, or congestive heart failure in the practices of 367 clinicians.
Data Collection/Extraction Methods:
Insurance payment system (PPD or FFS), hospitalizations, and office visits were obtained from patient reports. Disease and severity indicators, sociodemographics, and self-reported functional status were used to adjust for patient mix and to compute expected utilization rates.
Principal Findings:
Compared to FFS, PPD patients had 31 percent fewer observed hospitalizations before adjustment for patient differences (p = .005) and 15 percent fewer hospitalizations than expected after adjustment (p = .078). The observed rate of FFS hospitalizations exceeded the expected rate by 9 percent. These results are not explained by system differences in patient mix or trends in hospital use over four years. Half of the PPD/FFS difference in hospitalization rate is due to intrinsic characteristics of the payment system itself.
Conclusions:
PPD patients with chronic medical conditions followed prospectively over four years, after extensive patient-mix adjustment, had 15 percent fewer hospitalizations than their FFS counterparts owing to differences intrinsic to the insurance reimbursement system.
Related Concept Videos
Longitudinal Research
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
Documentation in Long-Term and Home Healthcare Setting
Long-Term Care Facilities
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Introduction to Epidemiology
Longitudinal Studies
