[Peritoneal blood flow, peritoneal transfer and continuous ambulatory peritoneal dialysis]

The aim of studies was an evaluation of effective peritoneal blood flow (EPBF) in patients treated with continuous ambulatory peritoneal dialysis (CAPD) and determination if there is a dependence between EPBF, peritoneal transfer and CAPD adequacy. In 14 patients (3 women and 11 men) treated with CAPD through 8.0 +/- 6.1 months the examinations of EPBF using diffusive peritoneal mass transfer coefficient of CO2, CAPD adequacy and peritoneal transfer during the first 2.5 minute dwell of dialysis solution in peritoneal cavity were performed. In 10 patients above mentioned examinations were repeated after 4.7 +/- 0.3 months of CAPD treatment. EPBF after 14 +/- 6.2 months of CAPD treatment showed increasing tendency (460 +/- 250 ml/min) comparing to values obtained at the beginning of treatment (285 +/- 150 ml/min). There was no significant dependence on peritoneal transfer rates of small molecules (sodium, potassium, urea and uric acid) in first 2.5 minutes dwell of dialysis solution in peritoneal cavity on EPBF. At EPBF greater than 200 ml/min excretion of total protein with dialysate and clearances of urea and creatinine showed positive dependence on EPBF. The obtained results indicate that both transperitoneal excretion of total protein and CAPD adequacy are dependent on peritoneal blood flow.