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Pancreatic duct stones management
J Devière1, M Delhaye, M Cremer
1Department of Gastroenterology, ULB Hopital Erasme, Free University of Brussels, Belgium.
Gastrointestinal Endoscopy Clinics of North America
|February 14, 1998
Summary
Pancreatic stone formation causes pain in chronic pancreatitis due to ductal obstruction. This review covers the causes of stones and current non-surgical treatments.
Area of Science:
- Gastroenterology
- Pancreatology
Background:
- Pancreatic stone formation is a hallmark of chronic pancreatitis.
- Ductal obstruction is a primary cause of pain and disability in chronic pancreatitis patients.
Purpose of the Study:
- To review the pathophysiology of pancreatic stone formation.
- To describe current nonsurgical therapeutic options for pancreatic stones.
Main Methods:
- Literature review of pathophysiology.
- Review of nonsurgical treatment modalities.
Main Results:
- Pancreatic stones result from chronic inflammation and ductal changes.
- Nonsurgical treatments focus on pain management and preventing further stone formation.
Conclusions:
- Understanding pancreatic stone pathophysiology is key to managing chronic pancreatitis.
- A range of nonsurgical therapies exist to alleviate symptoms and disease progression.