[Lipid components of aminoacyl-tRNA synthetase complex in eukaryotes and their function]

This review includes data about lipids composition of eukariotic high molecular complex of aminoacyl-tRNA synthetases under normal conditions and under the effect of ionizing radiation. The role of different lipids in formation of the structure of high molecular complex and functioning is discussed. The role of different groups of phospholipids, prostaglandins in providing the normal work of high molecular complex and some synthetases in control and pathological state is considered. A conclusion has been made that different groups of lipids composed the high molecular complex aminoacyl-tRNA synthetases. Some of them play structural role and other (prostaglandins, some phospholipids) are the regulatory components of the complex.