Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adrenaline degradation in general practice

S V Rudland1, T Annus, J Dickinson

  • 1Department of Biochemistry, Fremantle Hospital, Western Australia.

The British Journal of General Practice : the Journal of the Royal College of General Practitioners
|February 17, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Light Pseudoscalar Bosons, Pair-Produced in Higgs Boson Decays in the Four-Electron Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

First Evidence for Mixing-Induced CP Violation in B_{s}^{0}→J/ψϕ(1020) Decays in pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

Observation of Suppressed Charged-Particle Production in Ultrarelativistic Oxygen-Oxygen Collisions.

Physical review letters·2026
Same author

Measurement of D^{0} Meson Photoproduction in Ultraperipheral Heavy Ion Collisions.

Physical review letters·2026
Same author

Observation of tWZ Production at the CMS Experiment.

Physical review letters·2026
Same author

First Exclusive Reconstruction of the B^{*+}, B^{*0}, and B_{s}^{*0} Mesons and Precise Measurement of Their Masses.

Physical review letters·2026
Same journal

Learning disability register enrolment in young people in England: Cohort Study, 2015-2023.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Disparities in the uptake of learning disability (intellectual disability) annual health checks.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Recording of Pharmacy First consultations in general practice records in England: an observational study of the service's first year using OpenSAFELY.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

"I have no idea who does the bone thing" A qualitative exploration of older women and healthcare professionals' experiences to guide improvements in osteoporosis care.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Enriching New-onset Diabetes for Pancreatic Cancer (ENDPAC): External validation using English sentinel network.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same journal

Qualitative insights into identifying and managing polypharmacy: Patient, pharmacist and GP perspectives.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
See all related articles

General practitioners’ (GPs) drug storage in extreme temperatures reveals adrenaline stability. Despite regular checks, GPs often stock expired medications, impacting patient safety.

Area of Science:

  • Pharmacology
  • General Practice
  • Drug Stability

Background:

  • General practitioner (GP) doctor's bags are subject to significant temperature fluctuations.
  • These environmental conditions may compromise the stability and efficacy of essential medications carried by GPs.
  • Previous research indicated potential instability issues for drugs stored in such conditions.

Purpose of the Study:

  • To assess the stability of adrenaline (1:1000 solution) under conditions simulating a GP's doctor's bag.
  • To investigate the prevalence of expired medications being carried by general practitioners.
  • To evaluate the adherence of GPs to medication expiry date monitoring protocols.

Main Methods:

  • Stability testing of adrenaline (1:1000 solution) under simulated extreme temperature conditions.

Related Experiment Videos

  • Survey or audit of medications found in general practitioners' doctor's bags.
  • Analysis of self-reported medication checking practices among GPs.

    • Main Results:

    • Adrenaline (1:1000 solution) demonstrated greater stability than anticipated under tested extreme temperatures.
    • A notable proportion of general practitioners were found to be carrying medications past their expiry dates.
    • Discrepancies were observed between GPs' stated regular checks and the actual presence of out-of-date drugs.

    Conclusions:

    • Adrenaline (1:1000 solution) appears robust to temperature variations encountered in GP bags.
    • The practice of carrying expired drugs by GPs poses a potential risk to patient care.
    • Improved adherence to drug expiry date management is crucial for maintaining medication safety in primary care settings.