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Related Experiment Videos

Acute enteritis associated with reovirus-like agents

J Gomez-Barreto, E L Palmer, A J Nahmias

    JAMA
    |April 26, 1976
    PubMed
    Summary
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    Reovirus-like agents (RLAs) were identified in children with acute enteritis in Atlanta. Evidence suggests RLAs can cause infections in both children and adults.

    Area of Science:

    • Virology
    • Pediatrics
    • Gastroenterology

    Background:

    • Reovirus-like agents (RLAs) are a known cause of acute enteritis in children globally.
    • Previous studies indicated a high prevalence of RLAs in pediatric gastroenteritis cases worldwide.

    Purpose of the Study:

    • To investigate the presence and seroprevalence of RLAs in acute enteritis cases in Atlanta.
    • To determine if RLAs infections occur in adults.

    Main Methods:

    • Simplified electron microscopy was used to detect RLAs in stool samples.
    • Complement fixation tests were employed to assess antibody responses to RLA antigens.

    Main Results:

    • RLAs were detected in 16 of 29 children with acute enteritis.

    Related Experiment Videos

  • Antibody titer rises confirmed RLA infection in seven children and two mothers.
  • High seroprevalence of past RLA infection was observed, particularly in children aged 6 months to 4 years.

    • Conclusions:

    • RLA infections are prevalent in children with acute enteritis in Atlanta.
    • The findings suggest that RLAs can also cause infections in adults.
    • This study supports global observations of RLA-associated enteritis.