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Related Experiment Videos

Delayed-interval delivery in multifetal pregnancy

R P Porreco1, E D Sabin, K D Heyborne

  • 1Rocky Mountain Perinatal Associates, P.C. Columbia-HealthONE Perinatal Services, Denver, CO, USA.

American Journal of Obstetrics and Gynecology
|February 18, 1998
PubMed
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Delayed-interval delivery for selected multiple births can improve survival. This approach, with a mean latency of 34 days, reduced perinatal mortality in retained fetuses.

Area of Science:

  • Maternal-Fetal Medicine
  • Perinatology
  • Obstetrics

Background:

  • Delayed-interval delivery (DID) is a strategy for managing multiple gestations where delivery of one or more fetuses is postponed.
  • Selecting appropriate candidates for DID is crucial for optimizing outcomes in high-risk pregnancies.

Observation:

  • A retrospective review identified 59 cases of twins or triplets delivered before 30 weeks' gestation.
  • Sixteen pregnancies were deemed candidates for DID, with 9 cases having delivery intentionally delayed.
  • The mean latency interval in attempted DID cases was 34 days (range: 3-76 days).

Findings:

  • Candidates for DID were significantly less mature at presentation compared to those delivered immediately.
  • Perinatal mortality was significantly lower in fetuses managed with DID.

Related Experiment Videos

  • Exclusion criteria for DID included monochorionicity, abruptio placentae, severe preeclampsia, and need for hysterotomy.

    • Implications:

    • Selected cases of multichorionic pregnancies may benefit from a delayed-interval delivery approach.
    • Implementing modest intervals between sibling deliveries during critical gestational ages can enhance newborn survival.
    • Delayed-interval delivery can decrease neonatal morbidity in carefully selected multiple gestations.