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Time reversal in biological systems

M L Glassman1, A Hochberg

  • 1Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Israel.

Medical Hypotheses
|February 18, 1998
PubMed
Summary
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Carcinogenesis, or tumor development, mirrors biological evolution in a closed system. This process conceptually reverses biological order and evolutionary time, akin to time reversal symmetry in physics.

Area of Science:

  • Integrates fundamental physics with biological processes.
  • Explores the hierarchical structure of science from particles to organisms.

Background:

  • Molecular biology relies on physical descriptors of macromolecules and chemical reactions.
  • Understanding biological complexity requires interdisciplinary approaches.

Purpose of the Study:

  • To relate the physics concept of time reversal symmetry to biological processes.
  • To examine tumor development and progression through an evolutionary lens.

Main Methods:

  • Conceptual framework linking physics principles to biological phenomena.
  • Analogy of carcinogenesis as a microcosm of evolution within an individual organism.

Main Results:

  • Carcinogenesis exhibits driving forces of selection similar to evolutionary lineage.

Related Experiment Videos

  • Tumor development can lead to the emergence of a 'new biological species' with reproductive immortality.

    • Conclusions:

    • Carcinogenesis, as a closed system, conceptually represents a reversal of biological order and evolutionary time.
    • Malignancy's characteristics echo those of unicellular ancestors, suggesting a return to primordial states.