Related Experiment Videos
Effects of amphetamine on the development of Moloney sarcoma virus-induced tumors in mice
M Freire-Garabal1, M J Nuñez-Iglesias, M Rey-Méndez
1Department of Pharmacology, School of Pharmacy, University of Santiago de Compostela, Campus Sur, Santiago de Compostela, 15706, Spain.
Oncology Reports
|May 15, 1998
Abstract:
Experiments were conducted to evaluate the effects of amphetamine (0. 4 mg/kg) on the development of autochthonous tumors induced by the Moloney sarcoma virus (MSV) in Balb/c female mice. Enhancement of MSV-induced tumor incidence and tumor growth was observed, together with a delay in the usual prompt regression of the tumors, when mice were daily injected with amphetamine for 3 days after MSV-inoculation. However, no effects of amphetamine on tumor development were observed when it was administered during the 3 days before tumor inoculation.