Arrhythmia curve interpretation using a dynamic system model of the myocardial pacemaker
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Published on: May 23, 2021
N Ikeda1, K Takayanagi, A Takeuchi
1School of Allied Health Sciences, Kitasato University, Kanagawa, Japan. ikeda@kitasato-u.ac.jp
Abstract:
A problem of identifying the phase response curve of the myocardial pacemaker was investigated using a simple dynamic system model of cardiac arrhythmia. A hybrid optimization method of a genetic algorithm and a local optimization technique was employed to obtain a solution of the model fitting. The method was applied to two categories of arrhythmias, ventricular parasystole and high-degree AV block. The present study offered a new insight into the mechanism of cardiac arrhythmias.
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