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Related Experiment Videos

The Dentin Disc surface: a plausible model for dentin physiology and dentin sensitivity evaluation

D G Gillam1, N J Mordan, H N Newman

  • 1Department of Periodontology, Eastman Dental Institute for Oral Health Care Sciences, University of London, United Kingdom.

Advances in Dental Research
|February 21, 1998
PubMed
Summary

Dentin sensitivity (DS) can be treated by occluding open dentinal tubules. This study reviews methods for evaluating desensitizing agents in vitro, supporting tubule occlusion as a key mechanism for reducing sensitivity.

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Area of Science:

  • Dentistry
  • Biomaterials Science
  • Oral Biology

Background:

  • Dentin sensitivity (DS) affects 8-35% of the population, with no universally accepted desensitizing agent.
  • Brännström's Hydrodynamic Theory posits that open dentinal tubules are crucial for DS.
  • Tubule occlusion is a logical therapeutic strategy derived from the hydrodynamic theory.

Purpose of the Study:

  • To review in vitro evaluation methods for dentin desensitizing agents.
  • To assess the ability of agents to reduce dentin permeability via tubule occlusion.
  • To present findings from research using the Pashley Dentin Disc model.

Main Methods:

  • In vitro evaluation of desensitizing agents.
  • Characterization of agent effects on dentin surface.

Related Experiment Videos

  • Assessment of permeability reduction through tubule occlusion using the Pashley Dentin Disc model.

    • Main Results:

    • Many agents effective in reducing dentin permeability support the hydrodynamic theory.
    • The Pashley Dentin Disc model is a useful screening tool for evaluating desensitizing agents.
    • Observed in vitro changes require cautious extrapolation to clinical situations.

    Conclusions:

    • Tubule occlusion is a viable strategy for dentin desensitization.
    • In vitro models like the Pashley Dentin Disc model aid in screening potential desensitizing agents.
    • Further research is needed to correlate in vitro findings with clinical efficacy.