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A model of the inversion process in an arterial inversion experiment
K I Marro1, C E Hayes, M J Kushmerick
1Department of Radiology, University of Washington, Seattle 98195-7115, USA.
NMR in Biomedicine
|February 21, 1998
Summary
This study presents a model for spin behavior in arterial water during inversion experiments. The model accurately predicts inversion, aiding in optimizing MRI pulse sequences for in vivo applications.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Biophysics
Background:
- Accurate modeling of spin behavior is crucial for optimizing MRI techniques.
- Arterial spin labeling requires precise control over radiofrequency (RF) and gradient fields.
Purpose of the Study:
- To develop and validate a computational model for spin behavior in flowing arterial blood.
- To assess the model's ability to predict inversion efficiency in a two-coil arterial inversion experiment.
Main Methods:
- A biophysical model simulating adiabatic spin behavior in spatially varying gradient and B1 fields was developed.
- Model predictions were compared against experimental data from flow phantom studies.
- The study evaluated a range of gradient magnitudes, B1 field strengths, and flow velocities.
Main Results:
- The model demonstrated a high level of agreement with flow phantom results across various experimental parameters.
- The model successfully simulated the adiabatic behavior of arterial spins during inversion.
Conclusions:
- The validated model can assist in selecting efficient pulse sequence parameters for in vivo arterial inversion MRI.
- Insights from the model can guide the selection of optimal surface coil geometries for maximum inversion efficiency.