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[Microinvasive cervical cancer]

F Lécuru1, H Hoffman, C Mezan de Malartic

  • 1Service de Gynécologie-Obstétrique, Hôpital Boucicaut, Paris.

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|January 1, 1997
PubMed
Summary
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Microinvasive carcinoma (MIC) of the cervix is increasing in young women. Treatment focuses on conisation, with surgery adjusted based on invasion depth and lymphovascular invasion (LVI) to preserve function.

Area of Science:

  • Gynecologic Oncology
  • Cervical Pathology
  • Surgical Pathology

Context:

  • The incidence of microinvasive carcinoma (MIC) of the cervix is rising in women under 40.
  • MIC diagnosis relies on conisation following colposcopic biopsies for severe dysplasia or cervical neoplasia.
  • Established definitions and treatment protocols for MIC are evolving.

Purpose:

  • To review the diagnostic and therapeutic management of microinvasive carcinoma (MIC) in young women.
  • To emphasize the importance of accurate pathological evaluation, including stromal invasion depth and lymphovascular invasion (LVI).
  • To propose treatment strategies that balance oncological safety with functional preservation.

Summary:

  • Conisation is the standard surgical approach for MIC, provided clear margins.

Related Experiment Videos

  • Pathological assessment of stromal invasion depth (threshold 3 mm) and LVI is critical for treatment decisions.
  • If invasion exceeds 3 mm or LVI is present, treatment mirrors invasive cervical carcinoma; otherwise, conisation may suffice.

    • Impact:

    • This approach aims to optimize treatment for young women with MIC, reducing the risk of recurrence while preserving reproductive and sexual function.
    • Refined understanding of MIC can lead to more tailored surgical interventions.
    • Improved pathological assessment guides appropriate management, potentially avoiding more extensive surgery in select cases.