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[Malignant tumors of the peripheral nerve sheath (MPNST) after irradiation]
M Dini1, A Caldarella, G Lo Russo
1Cattedra di Chirurgia Plastica e Ricostruttiva, Istituto di Anatomiae Istologia Patologica, Università di Firenze.
Pathologica
|August 1, 1997
Abstract:
A case of relapsed malignant tumor of the brachial plexus and its nervous roots (MPNST) was observed in a patient treated with radiotherapy for Hodgkin's disease 24 years previously. A known risk of radiation therapy is the induction of secondary neoplasms, less commonly malignant peripheral nerve sheath tumor (MPNST). The clinico-pathological features of this rare tumor are presented and the possible relationship between radiotherapy and MPNST is discussed.