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Inhibition of lactation in rabbits by 2-Br-alpha-Ergokryptine-mesilate (CB154)
Arzneimittel-Forschung
|January 1, 1976
Abstract:
The lactating rabbit responds to single injections of the inhibitor of prolactin secretion 2-Br-alpha-ergokryptine-mesilate (CB 154) by a reversible reduction in milk yield, which is dose-dependent. Inhibition of galactopoiesis by CB 154 is also observed in rats, dogs, pigs and in woman, but not in goats and cattle. This points to a difference in prolactin dependence of galactopoiesis in the two groups.