[Acute renal insufficiency in hemorrhagic fever with renal syndrome]

In the Clinic for Nephrology of Military Medical Academy, 116 patients with hemorrhagic fever with renal syndrome (HFRS) have been treated in the period from January 1989 to December 1995. The patients were hospitalized with advanced acute renal failure (ARF). The largest number of our patients got ill from HFRS from the middle of March till the end of May and during August when the other frequency elevation was noticed. Most frequently the disease has the course that is followed up by phases. Positive finding of antibodies to HFRS virus was noticed in all 116 patients (Hantaan 45%, Belgrade 35%, Puumala 20%). According to clinical symptoms, signs and syndromes that follow up HFRS, the most of our patients were with more severe disease type. The ARF treatment with dialysis was necessary in 45% our patients. The most severe clinical forms were caused by Belgrade strain. Very favorable effect of "an early dialysis" to the disease course and outcome was observed. By this approach in HFRS therapy, the patient's mortality was decreased to 0.86%. The development of chronic renal failure as HFRS sequela is possible, but not so frequent.