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[Detection of Epstein-Barr virus DNA in malignant lymphomas]
1Vojnomedicinska akademija, ZPM-Institut za mikrobiologiju, Beograd.
Vojnosanitetski Pregled
|February 21, 1998
Abstract:
The etiology of malignant lymphomas is unknown, but certain evidence imply the possibility of Epstein-Barr virus connection to this disease. The presence of Epstein-Barr viral DNA in 95 patients with malignant lymphomas (49 patients with Hodgkin's disease and 46 patients with non-Hodgkin's lymphomas) was investigated by method of in situ hybridization. Viral DNA was proved in 30.53% patients with malignant lymphomas: in 38.78% of patients with Hodgkin's disease and 21.74% patients with non-Hodgkin's lymphomas. Those facts point out that Epstein-Barr virus is one of the possible carcinogens involved in those tumors growth.