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Bikunin and alpha 1-microglobulin in human zona pellucida and connective tissue
1Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Denmark.
The Histochemical Journal
|March 1, 1997
Abstract:
The occurrence of bikunin and alpha 1-microglobulin was investigated in human ovary and Fallopian tubes. Bikunin and alpha 1-microglobulin are transcribed in the liver from a common gene. Bikunin immunoreactivity was detected in the zona pellucida. A positive reaction for bikunin was also observed in connective tissue of the oviduct. In addition, mast cells showed a more intense positive reaction than the surrounding connective tissue. Specific displaceable alpha 1-microglobulin immunoreactivity was revealed in the zona pellucida. The data suggest that bikunin and alpha 1-microglobulin are trapped in the zona pellucida.