Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic opioids: a reassessment

M R Horning1

  • 1Rehabilitation Medicine Associates, Anchorage, Alaska 99508, USA.

Alaska Medicine
|February 25, 1998
PubMed
Summary
This summary is machine-generated.

Chronic opioid therapy for nonmalignant pain can be effective and safe. Careful patient selection and meticulous monitoring are key to managing addiction risks and side effects, balancing benefits against drawbacks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fibrodysplasia ossificans progressiva (myositis ossificans progressiva) treatment with disodium etidronate.

The Journal of pediatrics·1979
Same author

Neurogenic bowel management.

American family physician·1973
Same author

Latencies recorded by intramuscular needle electrodes in different portions of a muscle: variation and comparison with surface electrodes.

Archives of physical medicine and rehabilitation·1972
See all related articles

Area of Science:

  • Pharmacology
  • Pain Management
  • Addiction Psychiatry

Background:

  • Opioids are traditionally linked to addiction and antisocial behavior.
  • Recent evidence questions the blanket prohibition of chronic opioid use for nonmalignant pain.

Purpose of the Study:

  • To evaluate the pharmacologic profile and addiction potential of opioids in chronic nonmalignant pain.
  • To identify factors for successful and safe opioid utilization in this patient population.

Main Methods:

  • Review of pharmacologic properties of opioids.
  • Analysis of studies on opioid addiction and risk factors.
  • Examination of clinical experience with chronic opioid therapy for nonmalignant pain.

Main Results:

Related Experiment Videos

  • Opioids possess a favorable pharmacologic side effect profile.
  • Addiction risk is highly patient-dependent, not solely drug-dependent.
  • Successful use requires failure of other treatments, identification of risk factors, and meticulous management.

Conclusions:

  • Opioids can be used successfully for chronic nonmalignant pain with careful patient selection and monitoring.
  • The focus should be on balancing therapeutic benefits against side effects and addiction risks, not solely on dose.
  • Individualized treatment plans are crucial for optimizing outcomes in chronic pain management.