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Synthesis and antimicrobial activity of some new anilino benzimidazoles
M Tunçbilek1, H Göker, R Ertan
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Turkey.
Archiv Der Pharmazie
|February 25, 1998
Abstract:
A series of 2-(anilino or 2,6-dichloroanilino)-1,5(6)-disubstituted-1H-benzimidazoles (1-13) were prepared by reaction of several 2-chloro- or 2-chloromethyl-1H-benzimidazoles with aniline derivatives. The prepared compounds were screened for their in vitro antibacterial and antifungal activities. Compounds 2, 8, and 9 exhibited the best activity.