Effect of experimental selenium deficiency and its supplementation on lymphoid organs

Feeding of selenium deficient diet to albino rats for 75 days resulted in increased levels of plasma and adrenal glucocorticoids and atrophy of spleen and thymus. Supplementing the diet with selenium for 30 days resulted in recovery of atrophy of spleen and thymus; plasma and adrenal glucocorticoid levels were also restored back to the normal.