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Published on: August 28, 2020
Clinical perspectives in primary nocturnal enuresis
G A Gimpel1, W J Warzak, B R Kuhn
1Utah State University, Logan, USA.
Insights
Primary nocturnal enuresis (PNE) treatment options are reviewed. Enuresis alarms are recommended for families able to adhere to protocols, while desmopressin offers a safe, fast-acting alternative for pediatric bedwetting.
Area of Science:
- Pediatric Urology
- Sleep Medicine
- Behavioral Pediatrics
Background:
- Primary nocturnal enuresis (PNE) is a common pediatric condition.
- Awareness of current research on PNE etiology and treatment varies among professionals.
Purpose of the Study:
- To provide a comprehensive overview of PNE, focusing on etiology, evaluation, and treatment.
- To discuss the most current PNE treatments and their recent research findings.
Main Methods:
- Literature review of PNE etiology and evaluation.
- Analysis of current treatment options: imipramine, desmopressin acetate arginine vasopressin, and enuresis alarms.
- Evaluation of recent research on treatment effectiveness, long-term efficacy, cost, and safety.
Main Results:
- Enuresis alarms are identified as the treatment of choice for compliant families due to long-term efficacy, cost, and safety.
- Desmopressin acetate arginine vasopressin is a safe alternative with rapid response and ease of administration.
Conclusions:
- Treatment selection for PNE should consider family capability, desired response time, and administration ease.
- Enuresis alarms and desmopressin represent effective, evidence-based options for managing pediatric primary nocturnal enuresis.
Abstract:
Primary nocturnal enuresis (PNE) is prevalent among the pediatric population, but not all professionals are aware of the current research regarding the etiology and treatment of this disorder. This paper presents a broad overview of PNE, including etiology and evaluation, with a specific emphasis on treatment issues. The most current treatments (imipramine, desmopressin acetate arginine vasopressin, enuresis alarms) are discussed, including recent research on their effectiveness. In considering the recent data on long-term efficacy, overall cost, and safety, the treatment of choice appears to be the enuresis alarm for those families who are capable of following protocols. Desmopressin acetate arginine vasopressin is a safe alternative that has the advantage of quick response and ease of administration.
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