[Incidence of allergic diseases and atopic markers in a tertiary hospital]

R Rodríguez Medina1, M I Rojo Gutiérrez, M Becerril Angeles

  • 1Departamento de alergia e inmunología clínica, Hospital de Especialidades, CMN La Raza, Instituto Mexicano del Seguro Social.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|April 16, 1998
PubMed

Insights

This study on allergic disorders in Mexico City found high rates of Staphylococcus aureus and eosinophilia, particularly in children. Findings highlight a strong family history link and suggest these factors are associated with allergic conditions.

Area of Science:

  • Allergy and Immunology
  • Clinical Medicine
  • Epidemiology

Context:

  • Allergic disorders represent a significant global health burden.
  • Understanding their distribution and features is crucial for effective healthcare planning.
  • Mexico City, a major urban center, presents a unique demographic for such studies.

Purpose:

  • To describe the distribution and characteristics of allergic disorders.
  • To identify key clinical and demographic features in a tertiary hospital setting.
  • To investigate associations between eosinophilia, Staphylococcus aureus, and family history in allergic patients.

Summary:

  • A one-year descriptive study analyzed 1486 patients, with a near-equal gender distribution and a peak incidence in children under 10.
  • Peripheral and nasal eosinophilia were prevalent (57.6% and 58.1%, respectively).
  • High rates of Staphylococcus aureus (55% in positive throat cultures) and significant atopic family history (44%) were observed, with rhinitis and asthma being the most common diagnoses.

Impact:

  • The study identifies a high prevalence of Staphylococcus aureus and eosinophilia in patients with allergic disorders.
  • It underscores the importance of family history in the development of allergies.
  • Findings provide valuable data for allergy management and research in Mexico City.

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...