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Acute poisoning with clenbuterol--a case report
1Ist Department of Internal Diseases and Acute Poisonings, Medical Academy in Gdańsk.
Przeglad Lekarski
|January 1, 1997
Summary
This case report details acute clenbuterol intoxication in a bodybuilder. Prompt treatment with propranolol and potassium chloride successfully resolved severe symptoms and biochemical imbalances.
Area of Science:
- Pharmacology
- Toxicology
- Sports Medicine
Background:
- Clenbuterol, a selective beta 2-agonist, is misused by athletes for performance enhancement.
- Bodybuilders often use clenbuterol to increase muscle mass and reduce body fat.
Observation:
- A 21-year-old bodybuilder ingested 4.8g of clenbuterol, resulting in acute intoxication.
- Symptoms included tachycardia (160 bpm), headache, dizziness, tremor, sweating, weakness, and agitation.
- Biochemical abnormalities noted were hypokalemia (2.6 mmol/L) and hyperglycemia (18.7 mmol/L).
Findings:
- Intravenous administration of propranolol (1.0 mg) and potassium chloride (60 mmol) rapidly reversed symptoms.
- All clinical and biochemical abnormalities resolved within five hours of treatment.
Implications:
- This case highlights the dangers of clenbuterol misuse in athletic populations.
- Increased awareness and monitoring of clenbuterol use among athletes are warranted.
- Physicians should be vigilant for clenbuterol intoxication in patients presenting with related symptoms.