Treating depression through the therapeutic nurse-client relationship
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Updated: Oct 30, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
1Syracuse University College of Nursing, Syracuse, New York, USA.
Abstract:
This article provides a blueprint to guide the nurse's work with the client whose depression interferes with his or her health. It is based on an expanded version of Peplau's interpersonal theory and illustrates systematic assessment and intervention through the therapeutic nurse-client relationship. Differentiation of depression from related health problems and criteria for referral to a mental health professional such as a psychiatric-mental health advanced practice nurse are outlined. Practical interventions through the therapeutic relationship are illustrated to guide the nurse in working directly with the depressed client.
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