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[Enzyme immunoassay for the determination of serotonin in stored platelet concentrates]
I Ganschow1, H P Benn, R Fischer
1Abteilung für Transfusionsmedizin, Universitätsklinikum Eppendorf, Hamburg, Deutschland.
Beitrage Zur Infusionstherapie Und Transfusionsmedizin = Contributions to Infusion Therapy and Transfusion Medicine
|January 1, 1994
Abstract:
A new enzyme immunoassay (EIA) was applied on measurements of serotonin (5-HT) in stored platelet concentrates (PC). PC were prepared by apheresis of two separators (Cobe, Fresenius) or from buffy coats and stored for a period of 7 days at 22 degrees C and agitating. Measurements were done in pellets and suspension medium (plasma). Detection of 5-HT was specific and sensitive within the bounds of 2 and 1,000 ng/10(9) PLT.