[Glutamate oxalacetate and glutamate pyruvate aminotransferase activity in Streptomyces hygroscopicus 155 producing antibiotic complex]
Related Experiment Video
Updated: Oct 30, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
Published on: January 13, 2017
V A Chipeva1, I V Ivanova, B Gocheva
1National Collection of Microorganisms and Cell Cultures, Sofia, Bulgaria.
Abstract:
Antibiotic activity, aminotransferase activity and composition of intracellular amino acids in low and high potent variants of Streptomyces hygroscopicus 155 were studied. The data of the study are indicative of some general regularities characteristic of amino acid metabolism in actinomycetes: an increased pool of the main aminodonor amino acids (alanine, asparaginic and glutaminic acids) and an increased activity of aminotransferases in the cultures of both the variants when grown in media with readily assimilable nitrogen sources.
Related Concept Videos
Production of Antibiotics
Production of Organic Acids
Amino Acid Biosynthetic Pathways
