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Updated: Jul 28, 2026
17:28
Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Published on: June 17, 2015
Immunotoxicology: hazard identification and risk assessment
1Covance Laboratories, Inc.
Nutrition Reviews
|March 3, 1998
Summary
Immunotoxicology studies the immune system
Area of Science:
- Immunotoxicology: The study of environmental toxicants' effects on the immune system.
Background:
- Established link between suppressed immune function and altered host defense.
- Over 20 years of laboratory animal studies inform this field.
Purpose of the Study:
- To define immunotoxicology and its scope.
- To review the current state of knowledge and future challenges.
Main Methods:
- Review of laboratory animal studies.
- Analysis of rodent-based screening approaches.
Main Results:
- Demonstrated association between chemical exposure and immune suppression.
- Rodent models provide valuable, albeit limited, data.
Conclusions:
- Future research should focus on human exposure studies.
- Improved risk assessment for immunotoxicology is needed.
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