Monitoring diabetic control in developing countries: a review of glycated haemoglobin and fructosamine assays

Measurement of glycated proteins, especially haemoglobins, is now a routine procedure for monitoring previous glycaemic control in diabetic patients in the developed world. Until recently, however, the assays were sophisticated and costly and, therefore, were only rarely used in developing countries. With easier and cheaper tests now available, the measurement of glycaemic control could be also introduced into regional hospitals in developing countries. This paper reviews feasible methods for clinical laboratories with limited resources. Recent experiences from African countries are included.