Host cell signalling during Listeria monocytogenes infection

Macrophages and other mammalian cells respond to infection with Listeria monocytogenes by the transient or persistent activation of host cell signal transduction pathways. In addition, L. monocytogenes infection influences expression of various host cell genes, some of which may hinder or favour bacterial replication. The observed host cell responses vary with the different subcellular locations inhabited by L. monocytogenes during its intracellular life cycle.