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Interaction of reactive oxygen species with DNA. A review
1Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia. peskin@ibrran.msk.su
Biochemistry. Biokhimiia
|March 3, 1998
Abstract:
Data on direct and indirect effects of reactive oxygen species on DNA are reviewed. The classification of the types of DNA oxidative damage and repair enzymes including glycosylases and endo- and exonucleases is presented. The regulatory function of reactive oxygen species and their role in carcinogenesis are discussed.