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Updated: Oct 14, 2026

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
Published on: May 11, 2015
Recurrence of pulmonary hypertension after ventricular septal defect closure and perioperative response to nitric
G B Luciani1, R Pessotto, A Mazzucco
1Division of Cardiac Surgery, University of Verona, Italy.
Abstract:
The ability of inhaled nitric oxide to reduce pulmonary vascular resistance is currently used to select borderline patients for reparative surgery and to treat postoperative crises of pulmonary hypertension. A case of an infant with non-restrictive VSD who classified as a nitric oxide responder both in the catheterization laboratory and after surgery, but developed recurrent pulmonary hypertension is described. The limitations of inhaled nitric oxide in predicting the natural history of successfully operated patients are discussed.
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