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Clozapine: a mimicry of phaeochromocytoma
1Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
The Australian and New Zealand Journal of Psychiatry
|March 4, 1998
Abstract
Objective:
To report a case of clozapine-induced hypertension with raised urinary catecholamines.
Clinical Picture:
A 27-year-old man fulfilling DSM-III-R criteria for catatonic schizophrenia was treated with clozapine. He later developed both hypertension and raised urinary catecholamines which mimicked phaeochromocytoma.
Treatment:
Clozapine was withdrawn.
Outcome:
Both blood pressure and urinary catecholamines normalised.
Conclusions:
Clozapine may induce sympathetic hyperactivity.