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Related Experiment Videos

Lateral preference in post-traumatic stress disorder

B Spivak1, M Segal, R Mester

  • 1Research Unit, Ness Ziona Mental Health Center, Israel.

Psychological Medicine
|March 4, 1998
PubMed
Summary
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Combat veterans with post-traumatic stress disorder (PTSD) show significantly more mixed lateral preference, suggesting potential brain hemispheric imbalance. This finding may offer insights into the underlying mechanisms of PTSD.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Human Behavior

Background:

  • Investigated lateral preference in male patients diagnosed with combat-related post-traumatic stress disorder (PTSD).
  • Included 80 male PTSD patients and 100 healthy, age-matched male controls for comparison.

Purpose of the Study:

  • To assess and compare patterns of lateral preference between individuals with PTSD and healthy controls.
  • To explore potential links between lateral preference and the neurobiological underpinnings of PTSD.

Main Methods:

  • Utilized the Edinburgh Handedness Inventory-Modified and the Coren Inventory of Lateral Preference.
  • Examined preferences for hand, foot, eye, and ear dominance in all participants.

Main Results:

Related Experiment Videos

  • A significantly higher prevalence of mixed lateral preference was observed in PTSD patients (65%) compared to controls (43%).
  • Statistical analysis confirmed the significance of this difference (P < 0.005).

Conclusions:

  • Findings suggest a potential hemispheric imbalance, characterized by reduced lateralization, in individuals with PTSD.
  • This imbalance, possibly involving increased right-hemisphere activity, may be implicated in the pathophysiology and symptomology of PTSD.