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Prospects for human papillomavirus vaccine development: emerging HPV vaccines
J F Hines1, S J Ghim, A B Jenson
1Department of Obstetrics and Gynecology, Brooke Army Medical Center, Fort Sam Houston, TX 78234-6200, USA. hinesjeff@aol.com
Current Opinion in Obstetrics & Gynecology
|March 4, 1998
Abstract:
This review concentrates on recent advances in human papillomavirus vaccine development. Strategies for prophylactic HPV subunit vaccines utilizing recombinantly synthesized, immunogenic virus-like particles are discussed. Therapeutic strategies focusing on the induction of cell-mediated immunity and gene manipulation for the treatment of established HPV-associated disease are also reviewed.