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Osteosarcoma of the larynx
J K Berge1, S B Kapadia, E N Myers
1Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh Medical Center, Pa, USA.
Archives of Otolaryngology--Head & Neck Surgery
|March 4, 1998
Summary
Osteosarcoma of the larynx is extremely rare, typically affecting men. This report details the first known case of laryngeal osteosarcoma in a woman, originating in the cricoid cartilage.
Area of Science:
- Oncology
- Pathology
Background:
- Malignant mesenchymal tumors of the larynx are rare, representing 0.3% to 1% of all laryngeal cancers.
- Osteosarcoma is an exceptionally rare subtype of laryngeal malignancy.
Observation:
- A literature review identified only 12 previously reported cases of laryngeal osteosarcoma, all in male patients.
- Laryngeal osteosarcoma can be primary, secondary to radiation therapy for squamous cell carcinoma, or metastatic.
Findings:
- This report presents the first documented case of primary laryngeal osteosarcoma occurring in a female patient.
- The tumor originated in the cricoid cartilage.
Implications:
- This case expands the known demographic of laryngeal osteosarcoma, highlighting its occurrence in women.
- Further research into the etiology and presentation of rare laryngeal cancers is warranted.