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Comparison of ejection fraction calculated by nine different volume calculation methods

I Beranek, R Moore, S Kim

    Radiology
    |September 1, 1976
    PubMed
    Summary

    Nine methods for calculating left ventricular ejection fraction (EF) were evaluated. For comparing groups, all methods were suitable, but only five, including a new cone model, are appropriate for individual patient comparisons.

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    Area of Science:

    • Cardiology
    • Medical Imaging

    Background:

    • Left ventricular ejection fraction (EF) is a key indicator of cardiac function.
    • Accurate EF calculation is crucial for diagnosing and managing heart conditions.
    • Various methods exist for EF calculation, but their suitability for different comparison types is not always clear.

    Purpose of the Study:

    • To evaluate the appropriateness of nine different methods for calculating left ventricular ejection fraction (EF).
    • To compare the suitability of these methods for both inter-group and inter-individual comparisons.
    • To introduce and assess a novel EF calculation method based on a cone mathematical model.

    Main Methods:

    • Single plane right anterior oblique ventriculography was performed on 50 patients (25 with normal contraction, 25 with akinesia/dyskinesia).

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  • Left ventricular ejection fraction (EF) was calculated using nine distinct methods.
  • A new method utilizing a cone mathematical model was included in the evaluation.

    • Main Results:

    • All nine tested methods were found to be appropriate for inter-group comparisons of EF.
    • For inter-individual comparisons, only five methods were deemed appropriate.
    • The five appropriate methods for inter-individual comparisons included those by Davila, Chapman, Dodge, Beranek, and the newly developed cone model method.

    Conclusions:

    • The choice of EF calculation method is critical and depends on the intended comparison type (inter-group vs. inter-individual).
    • The new cone model method, along with established methods by Davila, Chapman, Dodge, and Beranek, provides reliable EF values for individual patient assessment.
    • Further validation of these specific methods for inter-individual comparisons is recommended for clinical practice.