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Updated: Aug 12, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Serial long-term phlebography after documented lower leg thrombosis
Insights
This study shows that deep vein thrombosis (DVT) in the calf clears best. Vein recovery varies with occlusion extent, but normal venous structures often return after DVT.
Area of Science:
- Vascular Medicine
- Radiology
- Pathology
Background:
- Deep vein thrombosis (DVT) can lead to long-term venous damage.
- Understanding the phlebographic appearance of post-thrombotic veins is crucial for patient management.
Purpose of the Study:
- To describe the phlebographic findings in patients following deep vein thrombosis.
- To correlate phlebographic results with the extent and location of the initial thrombotic event.
Main Methods:
- Retrospective analysis of 86 phlebograms from 38 patients.
- Follow-up duration ranged from 2 weeks to 6 years post-thrombosis.
- Phlebographic patterns were assessed for vein clearance, occlusion, and structural restoration.
Main Results:
- Veins cleared earliest and most completely in calf-limited thrombosis.
- Totally occluded veins showed slower and less complete clearance compared to partially occluded or non-occluded veins.
- Post-thrombotic restoration of normal venous and valvular structures was frequently observed.
Conclusions:
- Phlebography is valuable in assessing DVT outcomes.
- Vein recanalization and structural repair are common sequelae of DVT.
- Observed phlebographic patterns correlate with pathological findings of intimal thickening post-thrombosis.
Abstract:
Representative phlebograms from a series of 38 patients (86 phlebograms) followed up from 2 weeks to 6 years after the initial thrombotic episode are presented. The veins cleared earliest and most completely in patients with thrombosis, limited to the calf. Totally occluded veins cleared more slowly and less completely than non- or partially occluded veins. Post-thrombotic restoration of normal venous and valvular structures was commonly seen. The authors describe a phlebographic pattern which corresponds to previously documented pathological material, illustrating intimal thickening as a sequel to organization of thrombi onto the walls of the veins.
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