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Bath-PUVA therapy in three patients with scleredema adultorum
C M Hager1, H A Sobhi, N Hunzelmann
1Department of Dermatology, University of Cologne, Germany.
Background:
Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective.
Objective:
Our purpose was to determine the effect of bath-PUVA therapy on SA.
Methods:
Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment.
Results:
All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm2). Ultrasonography showed significant reduction in both skin thickness and density.
Conclusion:
Bath-PUVA therapy appears to be effective in the treatment of SA.