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Related Experiment Videos

Plant cell suspension cultures: some engineering considerations

P M Kieran1, P F MacLoughlin, D M Malone

  • 1Biochemical Engineering Research Group, School of Biological Sciences, Dublin City University, Ireland. kieranp@ccmail.dcu.ie

Journal of Biotechnology
|March 6, 1998
PubMed
Summary

Plant cell cultures offer an alternative to traditional methods for producing valuable compounds. However, economic challenges, particularly related to engineering factors like shear sensitivity, have limited commercialization.

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Area of Science:

  • Biotechnology
  • Plant Sciences
  • Chemical Engineering

Background:

  • Higher plants produce valuable biochemicals for pharmaceuticals, pesticides, and fragrances.
  • Plant cell culture presents an alternative production method to traditional cultivation or chemical synthesis.
  • Significant industrial and academic interest exists in large-scale plant cell cultures for high-value substances.

Purpose of the Study:

  • To review the commercial development of plant cell culture technology.
  • To focus on engineering-related factors limiting industrial application.
  • To investigate the impact of shear sensitivity in plant cell suspension cultures.

Main Methods:

  • Review of commercial development in plant cell culture technology.
  • Analysis of engineering considerations impacting industrial application.

Related Experiment Videos

  • Examination of studies on shear sensitivity in plant cell suspension cultures.

    • Main Results:

    • Industrial application of plant cell suspension cultures has been limited by economic feasibility.
    • Biological and engineering factors contribute to economic challenges.
    • Recent studies suggest shear sensitivity may be less critical than previously assumed in some cases.

    Conclusions:

    • Economic feasibility remains a primary barrier to the commercialization of plant cell culture technology.
    • Engineering factors, including shear sensitivity, require careful consideration.
    • Further research may refine our understanding of shear sensitivity and its role in bioreactor design.