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Diagnostic problems in thromboembolism
Folia Haematologica (Leipzig, Germany : 1928)
|January 1, 1979
Summary
Blood tests cannot detect current venous thrombosis or a prethrombotic state. Direct thrombus visualization, like phlebography, is essential for diagnosis, though tests aid in identifying coagulation disorders.
Area of Science:
- Medical Diagnostics
- Hematology
- Vascular Medicine
Background:
- Venous thrombosis presents diagnostic challenges.
- The role of laboratory blood tests in diagnosing venous thrombosis is debated.
- Identifying a prethrombotic state remains difficult.
Purpose of the Study:
- To evaluate the diagnostic utility of blood tests for venous thrombosis.
- To emphasize the necessity of direct thrombus visualization.
- To clarify the role of coagulation profiles in thrombosis management.
Main Methods:
- Review of pathogenetic aspects and diagnostic problems in venous thrombosis.
- Emphasis on the value and limitations of blood tests.
- Discussion of direct thrombus demonstration methods, particularly phlebography.
Main Results:
- Blood tests are insufficient for detecting ongoing thrombosis.
- Blood tests cannot identify a prethrombotic state.
- Phlebography is highlighted as the preferred method for direct thrombus demonstration.
Conclusions:
- Direct demonstration of the thrombus is crucial for diagnosing venous thrombosis.
- Blood tests are valuable for assessing the 'coagulation profile'.
- Coagulation tests can help identify specific deficiencies like antithrombin III deficiency or subnormal fibrinolytic activity.